Research report 2005 - Friedrich Miescher Laboratory of the Max Planck Society
Intelligent Algorithms for the Analysis of Cellular Splicing Mechanisms
Maschinelles Lernen in der Biologie (Dr. Gunnar Rätsch)
Friedrich-Miescher-Laboratorium für biologische Arbeitsgruppen in der MPG, Tübingen
SummaryNovel technologies allow for many measurements on biological systems, leading to fast-growing amounts and variety of data. In order to tap the full potential of the available data a thorough analysis is demanded. Apart from the electronic data organisation, an efficient and automatic analysis is a great conceptual challenge. Using modern Machine Learning Methods, researchers at the Friedrich Miescher Laboratory are analysing for example the complex phenomenon of cellular messenger RNA splicing. Their particular interest is the prediction of alternative splicing and a deeper understanding of its regulation mechanisms.