Research report 2008 - Max Planck Institute for Heart and Lung Research

Can Sirtuins combat aging?

Authors
Bober, Eva
Departments
Summary
Sirtuins are highly conserved histon/protein deacetylases, which confer stress resistance and longevity. In mammals sirtuins are represented by a gene family that consists of seven genes, Sirt1 -Sirt7. In our project we investigate the molecular basis of sirtuin functions in mammals. The understanding of sirtuin function can contribute to developing new therapeutic strategies to combat and/or treat age-related diseases.

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