Research report 2023 - Max Planck Institute of Molecular Cell Biology and Genetics

A map to study the behavior of early pancreas cells

Grapin-Botton, Anne; Beydag-Tasöz, Belin Selcen

Max-Planck-Institut für molekulare Zellbiologie und Genetik, Dresden

Anne Grapin-Botton’s research group focuses on how single cells act communally to generate an organ. Together with colleagues from the Novo Nordisk Foundation at University of Copenhagen, she and her team used a special method to watch both the activity of the gene Neurogenin 3 and the protein it makes in human pancreas cells. The researchers developed a methodology that can link the dynamic behaviors of pancreatic cells observed in live imaging movies to all the genes they express. This will contribute to a better understanding of how the hormone-producing cells of the pancreas develop.


For the full text, see the German version.

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