Research report 2020 - Max Planck Institute for Infection Biology

More than a schematic: How we want to decipher immunological signaling pathways

Authors
Taylor, Marcus J.
Departments

Forschungsgruppe Visualisierung immunologischer Signalwege

Summary
Communication is key for our immune system. When pathogens attack our body, this information must be passed on and converted into activity. We investigate the signalling mechanisms of the innate immune system to create a fundamental understanding of the function of these signal transduction pathways. To do so, we visualised the formation of the myddosome: a supramolecular organizing center, which forms at immune receptors and controls signal transmission. Our results can help understanding the dynamic interaction of signaling substances in immune cells.

For the full text, see the German version.

Go to Editor View