Yearbook 2008

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The huge amount of DNA sequence data derived from a multitude of species, which is at our disposal today, allows comparative studies of genome evolution. Such studies afford to trace back the evolution of genomic DNA sequences and to single out and study the processes that play an important role in changing and shaping the genomes of mammals. The interaction of these processes with other cellular operations is now being investigated and better understood. more
The development of computational models for biological processes opens the possibility to predict new effects of virtual targeted perturbations that can in turn be validated by experimental observations. Such predictions are highly relevant for many practical applications, for example the development of new drugs. Through the last years, the Bioinformatics group has been developing different tools, methods, and databases that support the computational modeling of biological processes, such as the pathway integration database ConsensusPathDB and the modeling system PyBioS. more
This article is concerned with models of rotating bodies which are composed of fluid matter and whose internal structure is determined to a great extent by its own gravitational field. In particular, these models exhibit an equilibrium between attracting gravitational forces, repelling pressure and centrifugal forces. By virtue of this balance of forces the body takes on a typical shape: a figure of equilibrium. In the following it is described which principle physical and mathematical aspects arise and, moreover, the complexity of this field is demonstrated by means of a number of examples. more
In May 2008, the cluster „Atlas“ was inaugurated at the Albert Einstein Institute in Hannover and is now by far the largest computing cluster for the gravitational wave community. It will play a major role in the first detection of gravitational waves in the near future. It made its first appearance in the Top 500 list of supercomputers on rank 58 and was – due to the efficient network setup – the fastest cluster that is based on Gigabit ethernet worldwide. more
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