Scientific Publications

Nusser, A.; Sagar; Swann, J.; Krauth, B.; Diekhoff, D.; Calderon, L.; Happe, C.; Grün, D.; Boehm, T.: Developmental dynamics of two bipotent thymic epithelial progenitor types. Nature (2022)

Hilgers, V.: Regulation of neuronal RNA signatures by ELAV/Hu proteins. Wiley interdisciplinary reviews: WIREs RNA, e1733 (2022)

Eilertz, D.; Mitterer, M.; Büscher, J. M.: automRm: An R Package for Fully Automatic LC-QQQ-MS Data Preprocessing Powered by Machine Learning. Analytical Chemistry (2022)

Jünger, F.; Ruh, D.; Strobel, D.; Michiels, R.; Huber, D.; Brandel, A.; Madl, J.; Gavrilov, A.; Mihlan, M.; Daller, C. C. et al.; Rog-Zielinska, E. A.; Römer, W.; Lämmermann, T.; Rohrbach, A.: 100 Hz ROCS microscopy correlated with fluorescence reveals cellular dynamics on different spatiotemporal scales. Nature Communications 13, 1758 (2022)

Paterson, N.; Lämmermann, T.: Macrophage network dynamics depend on haptokinesis for optimal local surveillance. eLife 11, e75354, pp. 1 - 32 (2022)

Bayer, M.; Grosschedl, R.: How to resist Notch-targeted T-leukemia therapy: Lineage- and MYC enhancer switch. Molecular Cell 82, pp. 884 - 886 (2022)

Mossad, O.; Batut, B.; Yilmaz, B.; Dokalis, N.; Mezö, C.; Nent, E.; Nabavi, L. S.; Mayer, M.; Maron, F. J. M.; Büscher, J. M. et al.; de Agüero, M. G.; Szalay, A.; Lämmermann, T.; Macpherson, A. J.; Ganal-Vonarburg, S. C.; Backofen, R.; Erny, D.; Prinz, M.; Blank, T.: Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N⁶-carboxymethyllysine. Nature Neuroscience 25, pp. 295 - 305 (2022)

Shvedunova, M.; Akhtar, A.: Modulation of cellular processes by histone and non-histone protein acetylation. Nature Reviews Molecular Cell Biology (2022)

Schönberger, K.; Obier, N.; Romero-Mulero, M. C.; Cauchy, P.; Mess, J.; Pavlovich, P. V.; Zhang, Y. W.; Mitterer, M.; Rettkowski, J.; Lalioti, M.-E. et al.; Jäcklein, K.; Curtis, J. D.; Féret, B.; Sommerkamp, P.; Morganti, C.; Ito, K.; Ghyselinck, N. B.; Trompouki, E.; Büscher, J. M.; Pearce, E. L.; Cabezas-Wallscheid, N.: Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity. Cell Stem Cell 29, pp. 131 - 148 (2022)

Groß, M.; Speckmann, C.; May, A.; Gajardo-Carrasco, T.; Wustrau, K.; Maier, S. L.; Panning, M.; Huzly, D.; Agaimy, A.; Bryceson, Y. T. et al.; Choo, S.; Chow, C. W.; Dückers, G.; Fasth, A.; Fraitag, S.; Gräwe, K.; Haxelmans, S.; Holzinger, D.; Hudowenz, O.; Hübschen, J.; Khurana, C.; Kienle, K.; Klifa, R.; Korn, K.; Kutzner, H.; Lämmermann, T.; Ledig, S.; Lipsker, D.; Meeths, M.; Naumann-Bartsch, N.; Rascon, J.; Schänzer, A.; Seidl, M.; Tesi, B.; Vauloup-Fellous, C.; Vollmer-Kary, B.; Warnatz, K.; Wehr, C.; Neven, B.; Vargas, P.; Sepulveda, F. E.; Lehmberg, K.; Schmitt-Gräff, A.; Ehl, S.: Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. The journal of allergy and clinical immunology: official publication of the American Academy of Allergy, Asthma and Immunology 149, pp. 388 - 399 (2022)

Mossad, O.; Nent, E.; Woltemate, S.; Folschweiller, S.; Büscher, J. M.; Schnepf, D.; Erny, D.; Staeheli, P.; Bartos, M.; Szalay, A. et al.; Stecher, B.; Vital, M.; Sauer, J. F.; Lämmermann, T.; Prinz, M.; Blank, T.: Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline. Nature aging 1, pp. 1127 - 1136 (2021)

Spohr, C.; Poggio, T.; Andrieux, G.; Schönberger, K.; Cabezas-Wallscheid, N.; Boerries, M.; Halbach, S.; Illert, A. L.; Brummer, T.: Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. (2021)

Challen, G. A.; Pietras, E. M.; Cabezas-Wallscheid, N.; Signer, R. A. J.: Simplified murine multipotent progenitor isolation scheme: Establishing a consensus approach for multipotent progenitor identification. Experimental Hematology 104, pp. 55 - 63 (2021)

Ibarra-Morales, D.; Rauer, M.; Quarato, P.; Rabbani, L.; Zenk, F.; Schulte-Sasse, M.; Cardamone, F.; Gomez-Auli, A.; Cecere, G.; Iovino, N.: Histone variant H2A.Z regulates zygotic genome activation. Nature Communications 12, 7002 (2021)

Castro Alvarez, J. J.; Revel, M.; Carrasco Sala, J.; Cléard, F.; Pauli, D.; Hilgers, V.; Karch, F.; Maeda, R. K.: Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference. PLoS Genetics 17 (11), e1009843 (2021)

Roy, R.; Ramamoorthy, S.; Shapiro, B. D.; Kaileh, M.; Hernandez, D.; Sarantopoulou, D.; Arepalli, S.; Boller, S.; Singh, A.; Bektas, A. et al.; Kim, J.; Moore, A. Z.; Tanaka, T.; McKelvey, J.; Zukley, L.; Nguyen, C.; Wallace, T.; Dunn, C.; Wersto, R.; Wood, W.; Piao, Y.; Becker, K. G.; Coletta, C.; De, S.; Sen, J. M.; Battle, A.; Weng, N.-p.; Grosschedl, R.; Ferrucci, L.; Sen, R.: DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity. Immunity 54, pp. 2465 - 2480 (2021)

Lalioti, M.-E.; Rettkowski, J.; Cabezas-Wallscheid, N.: Avoid shocking your hematopoietic stem cells to keep them young and growing. Cell Stem Cell 28, pp. 1887 - 1889 (2021)

Llaó-Cid, L.; Roessner, P. M.; Chapaprieta, V.; Öztürk, S.; Roider, T.; Bordas, M.; Izcue, A.; Colomer, D.; Dietrich, S.; Stilgenbauer, S. et al.; Hanna, B.; Martín-Subero, J. I.; Seiffert, M.: EOMES is essential for antitumor activity of CD8⁺ T cells in chronic lymphocytic leukemia. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 35, pp. 3152 - 3162 (2021)

Pessoa Rodrigues, C.; Chatterjee, A.; Wiese, M.; Stehle, T.; Szymanski, W. G.; Shvedunova, M.; Akhtar, A.: Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice. Nature Communications 12, 6212 (2021)

O’Meara, C. P.; Guerri, L.; Lawir, D.-F.; Mateos, F.; Iconomou, M.; Iwanami, N.; Soza-Ried, C.; Sikora, K.; Siamishi, I.; Giorgetti, O. B. et al.; Peter, S.; Schorpp, M.; Boehm, T.: Genetic landscape of T cells identifies synthetic lethality for T-ALL. Communications Biology 4, 1201 (2021)