Journal Article (3037)

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Loske, J.; Völler , M.; Lukassen, S.; Stahl, M.; Thürmann, L.; Seegebarth, A.; Röhmel, J.; Wisniewski, S.; Messingschlager, M.; Lorenz, S. et al.; Klages, S.; Eils, R.; Lehmann, I.; Mall , M. A.; Graeber, S. Y.; Trump, S.: Pharmacological Improvement of CFTR Function Rescues Airway Epithelial Homeostasis and Host Defense in Children with Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine (2024)
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Mishra, H.; Schlack-Leigers, C.; Lim, E. L.; Thieck, O.; Magg, T.; Raedler, J.; Wolf, C.; Klein, C.; Ewers, H.; Lee-Kirsch, M. A. et al.; Meierhofer, D.; Hauck, F.; Majer, O.: Disrupted degradative sorting of TLR7 is associated with human lupus. Science Immunology, eadi9575 (2024)
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van der Weijden, V. A.; Stötzel, M.; Iyer, D. P.; Fauler, B.; Gralinska, E.; Shahraz, M.; Meierhofer, D.; Vingron, M.; Rulands, S.; Alexandrov, T. et al.; Mielke, T.; Bulut-Karslioglu, A.: FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy. Nature Cell Biology (2024)
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Bulut-Karslioglu, A.: The double-edged sword of bivalency. Nature Reviews Molecular Cell Biology 25 (1), 6 (2024)
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Mitscherling, J.; Sczakiel, H. L.; Kiskemper-Nestorjuk, O.; Winterhalter, S.; Mundlos, S.; Bartzela, T.; Mensah, M. A.: Whole genome sequencing in families with oligodontia. Oral Diseases (2023)
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Zhou, W.; Fischer, A.; Ogwang, M. D.; Luo, W.; Kerchan, P.; Reynolds, S. J.; Tenge, C. N.; Were, P. A.; Kuremu, R. T.; Wekesa, W. N. et al.; Masalu, N.; Kawira, E.; Kinyera, T.; Otim, I.; Legason, I. D.; Nabalende, H.; Ayers, L. W.; Bhatia, K.; Goedert, J. J.; Gouveia, M. H.; Cole, N.; Hicks, B.; Jones, K.; Hummel, M.; Schlesner, M.; Chagaluka, G.; Mutalima, N.; Borgstein, E.; Liomba, G. N.; Kamiza, S.; Mkandawire, N.; Mitambo, C.; Molyneux, E. M.; Newton, R.; Glaser, S.; Kretzmer, H.; Manning, M.; Hutchinson, A.; Hsing, A. W.; Tettey, Y.; Adjei, A. A.; Chanock, S. J.; Siebert, R.; Yeager, M.; Prokunina-Olsson, L.; Machiela, M. J.; Mbulaiteye, S. M.: Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa. Nature Communications 14 (1), 8081 (2023)
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Basu, S.; Martínez-Cristóbal, P.; Frigolé-Vivas, M.; Pesarrodona, M.; Lewis, M.; Szulc, E.; Bañuelos, C. A.; Sánchez-Zarzalejo, C.; Bielskutė, S.; Zhu, J. et al.; Pombo-García, K.; Garcia-Cabau, C.; Zodi, L.; Dockx, H.; Smak, J.; Kaur, H.; Batlle, C.; Mateos, B.; Biesaga, M.; Escobedo, A.; Bardia, L.; Verdaguer, X.; Ruffoni, A.; Mawji, N. R.; Wang, J.; Obst, J. K.; Tam, T.; Brun-Heath, I.; Ventura, S.; Meierhofer, D.; García, J.; Robustelli, P.; Stracker, T. H.; Sadar, M. D.; Riera, A.; Hnisz, D.; Salvatella, X.: Rational optimization of a transcription factor activation domain inhibitor. Nature Structural & Molecular Biology 30 (12), pp. 1958 - 1969 (2023)
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Kost, C.; Patil, K. R.; Friedman, J.; Garcia, S. L.; Ralser, M.: Metabolic exchanges are ubiquitous in natural microbial communities. Nature Microbiology 8 (12), pp. 2244 - 2252 (2023)
29.
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Courraud, J.; Engel, C.; Quartier, A.; Drouot, N.; Houessou, U.; Plassard, D.; Sorlin, A.; Brischoux-Boucher, E.; Gouy, E.; Van Maldergem, L. et al.; Rossi, M.; Lesca, G.; Edery, P.; Putoux, A.; Bilan, F.; Gilbert-Dussardier, B.; Atallah, I.; Kalscheuer, V. M.; Mandel, J.-L.; Piton, A.: Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome. Molecular Psychiatry (2023)
30.
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Huang, X.; Henck, J.; Qiu, C.; Sreenivasan, V. K. A.; Balachandran, S.; Amarie, O. V.; de Angelis, M. H.; Behncke, R. Y.; Chan, W.-L.; Despang, A. et al.; Dickel, D. E.; Duran, M.; Feuchtinger, A.; Fuchs, H.; Gailus-Durner, V.; Haag, N.; Hägerling, R.; Hansmeier, N.; Hennig, F.; Marshall, C.; Rajderkar, S.; Ringel, A.; Robson, M. I.; Saunders, L. M.; da Silva-Buttkus, P.; Spielmann, N.; Srivatsan, S. R.; Ulferts, S.; Wittler, L.; Zhu, Y.; Kalscheuer, V. M.; Ibrahim, D. M.; Kurth, I.; Kornak, U.; Visel, A.; Pennacchio, L. A.; Beier, D. R.; Trapnell, C.; Cao, J.; Shendure, J.; Spielmann, M.: Single-cell, whole-embryo phenotyping of mammalian developmental disorders. Nature 623 (7988), pp. 772 - 781 (2023)
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Schifferl, D.; Scholze-Wittler, M.; Villaronga Luque, A.; Pustet , M.; Wittler, L.; Veenvliet, J. V.; Koch, F.: Genome-wide identification of notochord enhancers comprising the regulatory landscape of the Brachyury (T) locus in mouse. Development 150 (22), dev202111 (2023)
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Klever, M.-K.; Sträng , E.; Hetzel, S.; Jungnitsch, J.; Dolnik, A.; Schöpflin, R.; Schrezenmeier, J.-F.; Schick, F.; Blau, O.; Westermann, J. et al.; Rücker , F. G. ..; Xia, Z.; Döhner, K.; Schrezenmeier, H.; Spielmann, M.; Meissner, A.; Melo, U. S.; Mundlos, S.; Bullinger, L.: AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology. Blood Advances 7 (21), pp. 6520 - 6531 (2023)
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Rapakoulia, T.; Lopez Ruiz de Vargas, S.; Akbari-Omgba, P.; Laupert, V.; Ulitsky, I.; Vingron, M.: CENTRE: a gradient boosting algorithm for Cell-type-specific ENhancer-Target pREdiction. Bioinformatics 39 (11), btad687 (2023)
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Ravid Lustig, L.; Sampath Kumar, A.; Schwämmle, T.; Dunkel, I.; Noviello, G.; Limberg, E.; Weigert, R.; Pacini, G.; Buschow, R.; Ghauri, A. et al.; Stötzel, M.; Wittler, L.; Meissner, A.; Schulz, E. G.: GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. Nature Cell Biology 25, pp. 1704 - 1715 (2023)
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Petit, F.; Longoni, M.; Wells, J.; Maser, R. S.; Bogenschutz, E. L.; Dysart, M. J.; Contreras, H. T. M.; Frénois, F.; Pober, B. R.; Clark, R. D. et al.; Giampietro, P. F.; Ropers, H. H.; Hu, H.; Loscertales , M. ....; High, F. A.: PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects. The American Journal of Human Genetics 110 (10), pp. 1787 - 1803 (2023)
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de Sousa, J. A.; Wong, C.-W.; Dunkel, I.; Owens, T.; Voigt, P.; Hodgson, A.; Baker, D.; Schulz, E. G.; Reik, W.; Smith, A. et al.; Rostovskaya, M.; von Meyenn, F.: Epigenetic dynamics during capacitation of naïve human pluripotent stem cells. Science Advances 9 (39), eadg1936 (2023)
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Sultana, Z.; Dorel, M.; Klinger, B.; Sieber, A.; Dunkel, I.; Blüthgen, N.; Schulz, E. G.: Modeling unveils sex differences of signaling networks in mouse embryonic stem cells. Molecular Systems Biology, e11510 (2023)
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Jatzlau, J.; Mendez, P.-L.; Altay, A.; Raaz, L.; Zhang, Y.; Mähr, S.; Sesver, A.; Reichenbach, M.; Mundlos, S.; Vingron, M. et al.; Knaus, P.: Fluid shear stress-modulated chromatin accessibility reveals the mechano-dependency of endothelial SMAD1/5-mediated gene transcription. iScience 26 (9), 107405 (2023)
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Häfner, S. J.; Jansson, M. D.; Altinel, K.; Andersen, K. L.; Abay-Nørgaard, Z.; Ménard, P.; Fontenas, M.; Sørensen, D. M.; Gay, D. M.; Arendrup, F. S. et al.; Tehler, D.; Krogh, N.; Nielsen, H.; Kraushar, M. L.; Kirkeby, A.; Lund, A. H.: Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions. Developmental Cell 58 (17), pp. 1593 - 1609 (2023)
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Ng, M.; Verboon, L.; Issa, H.; Bhayadia, R.; Vermunt, M. W.; Winkler, R.; Schüler, L.; Alejo, O.; Schuschel, K.; Regenyi, E. et al.; Borchert, D.; Heuser, M.; Reinhardt, D.; Yaspo, M.-L.; Heckl, D.; Klusmann, J.-H.: Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15. iScience 26 (10), 107844 (2023)
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