Scientific Publications

Journal Article (98)

1.
Journal Article
Schutte, B. A. M.; van den Akker, E. B.; Deelen, J.; van de Rest, O.; van Heemst, D.; Feskens, E. J. M.; Beekman, M.; Slagboom, P. E.: The effect of standardized food intake on the association between BMI and (1)H-NMR metabolites. Sci Rep 6, p. 38980 (2016)
2.
Journal Article
Bonder, M. J.; Luijk, R.; Zhernakova, D. V.; Moed, M.; Deelen, P.; Vermaat, M.; van Iterson, M.; van Dijk, F.; van Galen, M.; Bot, J. et al.; Slieker, R. C.; Jhamai, P. M.; Verbiest, M.; Suchiman, H. E.; Verkerk, M.; van der Breggen, R.; van Rooij, J.; Lakenberg, N.; Arindrarto, W.; Kielbasa, S. M.; Jonkers, I.; van 't Hof, P.; Nooren, I.; Beekman, M.; Deelen, J.; van Heemst, D.; Zhernakova, A.; Tigchelaar, E. F.; Swertz, M. A.; Hofman, A.; Uitterlinden, A. G.; Pool, R.; van Dongen, J.; Hottenga, J. J.; Stehouwer, C. D.; van der Kallen, C. J.; Schalkwijk, C. G.; van den Berg, L. H.; van Zwet, E. W.; Mei, H.; Li, Y.; Lemire, M.; Hudson, T. J.; Consortium, B.; Slagboom, P. E.; Wijmenga, C.; Veldink, J. H.; van Greevenbroek, M. M.; van Duijn, C. M.; Boomsma, D. I.; Isaacs, A.; Jansen, R.; van Meurs, J. B.; t Hoen, P. A.; Franke, L.; Heijmans, B. T.: Disease variants alter transcription factor levels and methylation of their binding sites. Nat Genet 49 (1), pp. 131 - 138 (2016)
3.
Journal Article
Zhernakova, D. V.; Deelen, P.; Vermaat, M.; van Iterson, M.; van Galen, M.; Arindrarto, W.; van 't Hof, P.; Mei, H.; van Dijk, F.; Westra, H. J. et al.; Bonder, M. J.; van Rooij, J.; Verkerk, M.; Jhamai, P. M.; Moed, M.; Kielbasa, S. M.; Bot, J.; Nooren, I.; Pool, R.; van Dongen, J.; Hottenga, J. J.; Stehouwer, C. D.; van der Kallen, C. J.; Schalkwijk, C. G.; Zhernakova, A.; Li, Y.; Tigchelaar, E. F.; de Klein, N.; Beekman, M.; Deelen, J.; van Heemst, D.; van den Berg, L. H.; Hofman, A.; Uitterlinden, A. G.; van Greevenbroek, M. M.; Veldink, J. H.; Boomsma, D. I.; van Duijn, C. M.; Wijmenga, C.; Slagboom, P. E.; Swertz, M. A.; Isaacs, A.; van Meurs, J. B.; Jansen, R.; Heijmans, B. T.; t Hoen, P. A.; Franke, L.: Identification of context-dependent expression quantitative trait loci in whole blood. Nat Genet 49 (1), pp. 139 - 145 (2016)
4.
Journal Article
Wang, S.; Jacquemyn, J.; Murru, S.; Martinelli, P.; Barth, E.; Langer, T.; Niessen, C. M.; Rugarli, E. I.: The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying. PLoS Genet 12 (12), p. e1006463 (2016)
5.
Journal Article
Wai, T.; Saita, S.; Nolte, H.; Muller, S.; Konig, T.; Richter-Dennerlein, R.; Sprenger, H.-G.; Madrenas, J.; Muhlmeister, M.; Brandt, U. et al.; Kruger, M.; Langer, T.: The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep 17 (12), pp. 1844 - 1856 (2016)
6.
Journal Article
Wang, D.; Hou, L.; Nakamura, S.; Su, M.; Li, F.; Chen, W.; Yan, Y.; Green, C. D.; Chen, D.; Zhang, H. et al.; Antebi, A.; Han, J. J.: LIN-28 balances longevity and germline stem cell number in Caenorhabditis elegans through let-7/AKT/DAF-16 axis. Aging Cell 2017 Feb (16(1)), pp. 113 - 124 (2016)
7.
Journal Article
Slieker, R. C.; van Iterson, M.; Luijk, R.; Beekman, M.; Zhernakova, D. V.; Moed, M. H.; Mei, H.; van Galen, M.; Deelen, P.; Bonder, M. J. et al.; Zhernakova, A.; Uitterlinden, A. G.; Tigchelaar, E. F.; Stehouwer, C. D.; Schalkwijk, C. G.; van der Kallen, C. J.; Hofman, A.; van Heemst, D.; de Geus, E. J.; van Dongen, J.; Deelen, J.; van den Berg, L. H.; van Meurs, J.; Jansen, R.; t Hoen, P. A.; Franke, L.; Wijmenga, C.; Veldink, J. H.; Swertz, M. A.; van Greevenbroek, M. M.; van Duijn, C. M.; Boomsma, D. I.; consortium, B.; Slagboom, P. E.; Heijmans, B. T.: Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. Genome Biol 17 (1), p. 191 (2016)
8.
Journal Article
Koenig, T.; Troder, S. E.; Bakka, K.; Korwitz, A.; Richter-Dennerlein, R.; Lampe, P. A.; Patron, M.; Muhlmeister, M.; Guerrero-Castillo, S.; Brandt, U. et al.; Decker, T.; Lauria, I.; Paggio, A.; Rizzuto, R.; Rugarli, E. I.; De Stefani, D.; Langer, T.: The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria. Mol Cell 64 (1), pp. 148 - 162 (2016)
9.
Journal Article
Kauppila, J. H. K.; Baines, H. L.; Bratic, A.; Simard, M.-L.; Freyer, C.; Mourier, A.; Stamp, C.; Filograna, R.; Larsson, N.G.; Greaves, L. C. et al.; Stewart, J. B.: A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell Rep 16 (11), pp. 2980 - 90 (2016)
10.
Journal Article
Lalić, J.; Posavec Marjanović, M.; Palazzo, L.; Perina, D.; Sabljić, I.; Žaja, R.; Colby, T.; Pleše, B.; Halasz, M.; Jankevicius, G. et al.; Bucca, G.; Ahel, M.; Matić, I.; Ćetković, H.; Luić, M.; Mikoč, A.; Ahel, I.: Disruption of Macrodomain Protein SCO6735 Increases Antibiotic Production in Streptomyces coelicolor. J Biol Chem 291 (44), pp. 23175 - 23187 (2016)
11.
Journal Article
Djuardi, Y.; Supali, T.; Wibowo, H.; Heijmans, B. T.; Deelen, J.; Slagboom, P. E.; Houwing-Duistermaat, J. J.; Sartono, E.; Yazdanbakhsh, M.: Maternal and child cytokine relationship in early life is not altered by cytokine gene polymorphisms. Genes Immun 17 (7), pp. 380 - 385 (2016)
12.
Journal Article
Cross, B. C.; Lawo, S.; Archer, C. R.; Hunt, J. R.; Yarker, J. L.; Riccombeni, A.; Little, A. S.; McCarthy, N. J.; Moore, J. D.: Increasing the performance of pooled CRISPR-Cas9 drop-out screening. Sci Rep 6, p. 31782 (2016)
13.
Journal Article
Perez-Perez, R.; Lobo-Jarne, T.; Milenkovic, D.; Mourier, A.; Bratic, A.; Garcia-Bartolome, A.; Fernandez-Vizarra, E.; Cadenas, S.; Delmiro, A.; Garcia-Consuegra, I. et al.; Arenas, J.; Martin, M. A.; Larsson, N.G.; Ugalde, C.: COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation. Cell Rep 16 (9), pp. 2387 - 98 (2016)
14.
Journal Article
Tatsuta, T.; Langer, T.: Intramitochondrial phospholipid trafficking. Biochim Biophys Acta 1862 (1), pp. 81 - 89 (2016)
15.
Journal Article
Noordam, R.; Oudt, C. H.; Deelen, J.; Slagboom, P. E.; Beekman, M.; van Heemst, D.: Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age. Aging (Albany NY) 8 (8), pp. 1790 - 801 (2016)
16.
Journal Article
Kühl, I.; Miranda, M.; Posse, V.; Milenkovic, D.; Mourier, A.; Siira, S. J.; Bonekamp, N.; Neumann, U.; Filipovska, A.; Polosa, P. L. et al.; Gustafsson, C. M.; Larsson, N.G.: POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA. Sci Adv 2 (8), p. e1600963 (2016)
17.
Journal Article
von Schimmelmann, M.; Feinberg, P. A.; Sullivan, J. M.; Ku, S. M.; Badimon, A.; Duff, M. K.; Wang, Z.; Lachmann, A.; Dewell, S.; Ma'ayan, A. et al.; Han, M. H.; Tarakhovsky, A.; Schaefer, A.: Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration. Nat Neurosci 19 (10), pp. 1321 - 30 (2016)
18.
Journal Article
Hartmann, B.; Wai, T.; Hu, H.; MacVicar, T.; Musante, L.; Fischer-Zirnsak, B.; Stenzel, W.; Graf, R.; van den Heuvel, L.; Ropers, H. H. et al.; Wienker, T. F.; Hubner, C.; Langer, T.; Kaindl, A. M.: Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation. Elife 5 (2016)
19.
Journal Article
Rackham, O.; Busch, J. D.; Matic, S.; Siira, S. J.; Kuznetsova, I.; Atanassov, I.; Ermer, J. A.; Shearwood, A. M.; Richman, T. R.; Stewart, J. B. et al.; Mourier, A.; Milenkovic, D.; Larsson, N.G.; Filipovska, A.: Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly. Cell Rep 16 (7), pp. 1874 - 90 (2016)
20.
Journal Article
Rusli, F.; Deelen, J.; Andriyani, E.; Boekschoten, M. V.; Lute, C.; van den Akker, E. B.; Muller, M.; Beekman, M.; Steegenga, W. T.: Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice. Sci Rep 6, p. 30484 (2016)
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