Research report 2010 - Max Planck Institute for Neurobiology of Behavior - caesar

Ultra-fast freeze quenching of an activation process - A slide show of molecular movements

Authors
Peuker, Sebastian
Departments
Abteilung Molekulare Neurosensorik
caesar (center of advances european studies and research)
Summary
Receptors provide cells with all relevant information by perceiving cues of the environment. Inside a cell, the information is often transmitted by secondary messengers. Among the plethora of second messengers 3'-5'-cyclic adenosine monophosphate (cAMP) is the most important one. cAMP binds to specific target proteins thereby changing the protein's three-dimensional structure; the protein gets activated. We will study this structural change with high spatiotemporal resolution to learn more about the exact activation mechanism of this class of proteins.

For the full text, see the German version.

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