Master thesis "Development of cell-free enzyme cascade for in-vitro glycosylation"

Young Researchers Magdeburg
Structural and Cell Biology Chemistry Complex Systems

Job Code:

Job Offer from September 06, 2019

Background:

Glycosylation is an important modification of proteins, and is involved in the regulation of biological activity and stability of many proteins. Furthermore, glycosylated proteins play an important role in the development of therapeutics. At the MPI Magdeburg, in-vitro enzyme cascades are build up to synthesize defined glycoproteins. The focus of the project will be as follows:

 

-          Recombinant production of enzymes from the glycosylation machinery in microbial systems

-          Downstream Processing of enzymes and membrane proteins

-          Protein analytics and enzyme reactions with different reaction conditions

 

The candidates will have the opportunity to work on key technologies and use state-of-the-art equipment in an international group of researchers. In-depth supervision and training will be provided by MPI staff.

 

Requirements:

-          Background in Biotechnology, Technical Biology, Bioprocess Engineering, Bioengineering

-          Good experience of lab works and ideally, experience with one of the following techniques: protein expression, protein analytic, protein purification and molecular biology methods

-          Motivation, curiosity and team work skills

 

We offer:

-          Exciting research projects and the opportunity to develop key technologies

-          First-class supervision and thorough training by our staff

-          Training on state-of-the-art equipment for biotechnological research and development

-          Acquisition of expertise in a key technology of the future

 

Application:

Please send your application in German or English and include your CV and transcript of records to the contact.

The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds. Furthermore, the Max-Planck society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.

 

Start:

October/November 2019

 

Contacts:

Dr. Thomas Rexer

E-Mail: rexer@mpi-magdeburg.mpg.de

Phone: +49 (0) 391 6110 375

 

Lisa Wenzel, M.Sc.

E-Mail: wenzell@mpi-magdeburg.mpg.de

Phone: +49 (0) 391 6110 229

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