Research report 2017 - Associated Institute - Research Center caesar (center of advanced european studies and research)
Species-specific wiring of the mammalian retina
Assoziierte Einrichtung - Forschungszentrum caesar (center of advanced european studies and research), Bonn
SummaryAmongst mammalian species, the diameter of the eye varies by more than an order of magnitude. Objects in visual space traverse the surface of the retina of a large diameter eye at a higher velocity than that of a small diameter eye, raising the question of how different species encode the velocity of moving objects. Using comparative connectomics and computational modelling, we identified a difference in the placement of synapses among neurons in the mouse versus rabbit retina. Our results suggest an adaptation in neural wiring that compensates for eye diameter differences across species.