Research report 2017 - Associated Institute - Ernst Strüngmann Institute (ESI) for Neuroscience in Cooperation with Max-Planck-Society
Neuronal patterns and the formation of memory
Assoziierte Einrichtung - Ernst Strüngmann Institute (ESI) for Neuroscience, Frankfurt am Main
SummarySpontaneous activity patterns are strongly implicated in memory consolidation processes. Neuronal activity patterns and sensory responses depend strongly on behavioral state. Active behavioral states are associated with enhanced gain, the presence of fast cortical dynamics, and a reduction in spontaneous activity. Inactive behavioral states like sleep are associated with enhanced spontaneous activity, reduced response gain, and slow cortical dynamics that are temporally highly structured. These effects depend strongly on the activity of specific GABAergic interneurons.