Research report 2017 - Max Planck Institute of Experimental Medicine
Activity-independent neuronal network formation in the brain
Brose, Nils; Sigler, Albrecht; Imig, Cordelia; Altas, Bekir; Kawabe, Hiroshi; Cooper, Benjamin; Kwon, Hyung-Bae; Rhee, Jeong-Seop
SummaryAccording to the current dogma in neuroscience, neurons in the brain must communicate actively with each other to establish functional networks. Recent results now demonstrate that neurons in a brain region that is critically involved in learning and memory processes can connect and form structurally normal networks without active signal transmission at their synaptic contact points.