Research report 2017 - Max Planck Institute of Neurobiology

The unfolding of brain folding

Authors
Klein, Rüdiger
Departments
Abteilung Molecules - Signaling - Development
Summary
The cortex of the human brain is folded into an intricate pattern of grooves and furrows, which affords the cortex surface to be large, despite the small cranial space. But not all mammals have such a folded brain surface. By using a genetic manipulation, scientists at the Max-Planck Institute of Neurobiology have induced folds in the normally smooth surface of the mouse brain. The results have given insight into the underlying mechanisms that control brain folding.

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