Research report 2017 - Max Planck Institute of Molecular Physiology

Tracking hereditary processes with neo-functionalized proteins

Authors
Neumann, Heinz
Departments
Abteilung Strukturbiochemie
Summary
How the hereditary material in the cell nucleus is organized determines its flexibility in structure and composition that underlies the genetic processes. Researchers at the MPI of molecular Physiology developed methods using genetically encoded cross-linker amino acids to study chromatin changes in living cells. They have discovered an interaction between nucleosomes which contributes to the condensation of chromosomes during mitosis. In future studies, these methods will help to analyze hereditary processes during the cell cycle.

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