Research report 2016 - Max Planck Institute of Colloids and Interfaces
Nanoparticles interacting with Membranes and Vesicles
Agudo-Canalejo, Jaime; Lipowsky, Reinhard
Max-Planck-Institut für Kolloid- und Grenzflächenforschung, Potsdam-Golm
SummaryNanoparticles are tiny particles with sizes between a millionth and a thousandth of a millimeter. They include natural viruses, as well as synthetic particles that are increasingly used for medical purposes. In order to enter a cell via endocytosis, a nanoparticle must first bind to the outer cell membrane. The membrane then spreads onto the particle surface until the particle is completely engulfed by the membrane. The key parameters that control this process on nanoscopic length scales have only recently been identified.