Research report 2016 - Max Planck Institute of Immunobiology and Epigenetics

Enlightening organelle function - live cell imaging reveals insight into metabolic communication strategies of immune cells

Authors
Rambold, Angelika
Departments
Forschungsgruppe Organelle Communication Immunology
Summary
In response to pathogens, immune cells activate a cellular program to eliminate harmful, infectious organisms and ensure our health. To mount a functional immune response, most immune cells require the reprogramming of their metabolic pathways. The scientists aim at gaining novel insight into how specific cellular compartments, so-called organelles, regulate such metabolic transitions. Of particular interest is hereby not only the function of individual organelles but also how inter-organellar communication drives metabolic immune cell programs and enables the fight against infections.

For the full text, see the German version.

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