Yearbook 2016

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Synapses link individual neurons into a functional circuit. Proper cell-to-cell connection is therefore a fundamental mechanism for normal brain functions, and abnormal connections result in various forms of brain disorders or death. During early cortical development, each neuron elongates its axons and dendrites, forming synapses with both interneurons and excitatory neurons. Amazingly, these excitatory and inhibitory synapses are highly intermingled in dendrites with micron-precision, but the specific rules that govern this precise synaptic localization remain unknown. more
How species differ from each other is a key question in biology. But genetic mapping between species has been challenging, because hybrid crosses are typically sterile. Combining latest stem cell and genomic techniques, the research group has pioneered in vitro recombination to circumvent breeding and directly cause gene exchanges in cells. In this way they have mapped differences between mouse species within weeks and created mouse embryos carrying hybrid mosaic genomes. By circumventing species barriers that prevent interbreeding this work sheds light on the genetic basis of trait variation. more
Considering the reduction of greenhouse gas paramount target of “Energiewende” all sectors of the energy system are to be crosslinked. However, interlinkage will only be possible by converting primary electricity into material energy carriers. We are “storing” this electricity in order to make it available to other applications and so achieve the target of sector integration into sustainable energy supply. This article deals with the integration of mobility. For chemistry that means to develop sustainable alternatives to pure electrical driving. more
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