Research report 2015 - Max Planck Institute for Biology of Ageing
Studying adult stem cell regulation using skin as a model
Wickström, Sara A.
Max-Planck-Forschungsgruppe Homeostase und Alterung der Haut
SummaryHow complex but stereotyped tissues are formed, maintained and regenerated through local growth, differentiation and remodeling is a fundamental open question in biology. To answer this question we need to understand how single cell behaviors are coordinated on the population level and how population-level dynamics are coupled to tissue architecture. Uncovering these regulatory principles will further facilitate development of stem cell therapies and effective treatments to slow down ageing and prevent age-related diseases such as cancer.