Publikationen im Jahrbuch 2012

Jahrbuch
1.
Bibow, S.; Mukrasch, M.; Chinnathambi, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Mandelkow, E. M.;
The dynamic structure of filamentous tau. Angewandte Chemie International Edition 50, 11520-11524 (2011)
2.
Bibow, S.; Ozenne, V.; Biernat, J.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.;
Structural impact of proline-directed pseudo-phosphorylation at AT8, AT100 and PHF1 epitopes on 441-residue tau. Journal of the American Chemical Society 133, 15842-15845 (2011)
3.
Garg, S.; Timm, T.; Mandelkow, E. M.; Mandelkow, E.; Wang, Y.;
Cleavage of Tau by calpain in Alzheimer's disease: The quest for the toxic 17 kD fragment. Neurobiology of Aging 32, 1-14 (2011)
4.
Kachalova, G.; Decker, K.; Holt, A.; Bartunik, H. D.;
Crystallographic snapshots of the complete reaction cycle of nicotine degradation by an amine oxidase of the monoamine oxidase (MAO) family. PNAS 108, 4800-4805 (2011)
5.
Li, X.; Kumar, Y.; Zempel, H.; Mandelkow, E. M.; Biernat, J.; Mandelkow, E.;
Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration. The EMBO Journal 30, 4825-4837 (2011)
6.
Schirmer, R. H.; Adler, H.; Pickhardt, M.; Mandelkow, E.;
Lest we forget you - methylene blue. Neurobiology of Aging 32 (12), 2325.e7-2325.e16 (2011)
7.
Shkumatov, A; Chinnathambi, S.; Mandelkow, E.; Svergun, D. I.;
Structural memory of natively unfolded tau protein detected by Small-Angle X-ray Scattering. Proteins 79, 2122-2131 (2011)
8.
Sydow, A.; van der Jeugd, A.; Zheng, F.; Ahmed, T.; Balschun, D.; Petrova, O.; Drexler, D.; Zhou, L.; Rune, G.; Mandelkow, E.; d'Hooge, R.; Alzheimer, C.; Mandelkow, E. M.;
Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model. Journal of Molecular Neuroscience 45, 432-437 (2011)
9.
Sydow, A.; van der Jeugd, A.; Zheng, F.; Ahmed, T.; Balschun, D.; Petrova, O.; Drexler, D.; Zhou, L.; Rune, G.; Mandelkow, E.; d'Hooge, R.; Alzheimer, C.; Mandelkow, E.-M.;
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant. The Journal of Neuroscience 31, 2511-2525 (2011)
10.
Taghavi, A.; Nasir, S.; Pickhardt, M.; Heyny-von Haussen, R.; Krause, S.; Mall, G.; Mandelkow, E.; Mandelkow, E. M.; Schmidt, B.;
N´-benzylidene-benzohydrazides as novel and selective tau-PHF ligands. Journal of Alzheimer's Disease 27, 835-843 (2011)
11.
Timm, T.; von Kries, J. P.; Li, X.; Zempel, H.; Mandelkow, E.; Mandelkow, E. M.;
Microtubule affinity regulating kinase (MARK) activity in living neurons examined by a genetically encoded FRET/FLIM based biosensor: Inhibitors with therapeutic potential. The Journal of Biological Chemistry 286, 41711-41722 (2011)
12.
Wegmann, S.; Schöler, J.; Bippes, C. A.; Mandelkow, E.; Müller, D. J.;
Competing interactions stabilize pro- and anti-aggregant conformations of human tau. The Journal of Biological Chemistry 286, 20512-20524 (2011)
13.
Yamada, K.; Cirrito, J. R.; Stewart, F. R.; Jiang, H.; Finn, M. B.; Holmes, B.; Binder, L. I.; Mandelkow, E. M.; Diamond, M. I.; Lee, V. M. Y.; Holtzman, D. M.;
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. The Journal of Neuroscience 31, 13110-13117 (2011)
14.
Zempel, H.; Mandelkow, E. M.;
Linking Amyloid-β and Tau: Amyloid-β Induced Synaptic Dysfunction via Local Wreckage of the Neuronal Cytoskeleton. Neurodegenerative Diseases 10, 242-250 (2011-12-07)
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