Publikationen im Jahrbuch 2012
The dynamic structure of filamentous tau.
Angewandte Chemie International Edition 50, 11520-11524 (2011)
Structural impact of proline-directed pseudo-phosphorylation at AT8, AT100 and PHF1 epitopes on 441-residue tau.
Journal of the American Chemical Society 133, 15842-15845 (2011)
Cleavage of Tau by calpain in Alzheimer's disease: The quest for the toxic 17 kD fragment.
Neurobiology of Aging 32, 1-14 (2011)
Crystallographic snapshots of the complete reaction cycle of nicotine degradation by an amine oxidase of the monoamine oxidase (MAO) family.
PNAS 108, 4800-4805 (2011)
Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration.
The EMBO Journal 30, 4825-4837 (2011)
Lest we forget you - methylene blue.
Neurobiology of Aging 32 (12), 2325.e7-2325.e16 (2011)
Structural memory of natively unfolded tau protein detected by Small-Angle X-ray Scattering.
Proteins 79, 2122-2131 (2011)
Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model.
Journal of Molecular Neuroscience 45, 432-437 (2011)
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant.
The Journal of Neuroscience 31, 2511-2525 (2011)
N´-benzylidene-benzohydrazides as novel and selective tau-PHF ligands.
Journal of Alzheimer's Disease 27, 835-843 (2011)
Microtubule affinity regulating kinase (MARK) activity in living neurons examined by a genetically encoded FRET/FLIM based biosensor: Inhibitors with therapeutic potential.
The Journal of Biological Chemistry 286, 41711-41722 (2011)
Competing interactions stabilize pro- and anti-aggregant conformations of human tau.
The Journal of Biological Chemistry 286, 20512-20524 (2011)
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice.
The Journal of Neuroscience 31, 13110-13117 (2011)
Linking Amyloid-β and Tau: Amyloid-β Induced Synaptic Dysfunction via Local Wreckage of the Neuronal Cytoskeleton.
Neurodegenerative Diseases 10, 242-250 (2011-12-07)