Prof. Dr. Franz-Ulrich Hartl
Max-Planck-Institut für Biochemie, MartinsriedTelefon: +49 89 8578-2244
Fax: +49 89 8578-2211
E-Mail: uhartl@biochem.mpg.de
Medizin . Neurobiologie . Strukturbiologie . Zellbiologie
Protein folding: A perspective from theory and experiment.
Angew. Chem. Int. Ed. Engl. 37, 868–893 (1998).
Molecular chaperones in the cytosol: from nascent chain to folded protein.
Science 295, 1852–1858 (2002).
Adapting proteostasis for disease intervention.
Science 319, 916–919 (2008).
The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases.
EMBO J. 27, 336–349 (2008).
The stress of misfolded proteins: C. elegans models for neurodegenerative disease and aging.
Adv. Exp. Med. Biol. 594, 167–189 (2007).
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease.
Hum. Mol. Genet. 10, 1307–1315 (2001).
Development of tau aggregation inhibitors for Alzheimer’s disease.
Angew. Chem. Int. Ed. Engl. 48, 1740–1752 (2009).
The induction of heat shock proteins as a potential strategy to treat neurodegenerative disorders.
Drug News Perspect. 17, 299–306 (2004).
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